Principal Investigator
Dr. Janelle Drouin-Ouellet
Principal Investigator
I am an Associate Professor at the Université de Montréal, Canada, a neuroscientist, and a Canada Research Chair in Direct Neural Reprogramming. My research group works with direct neural reprogramming to study neurodegenerative disorders and identify new therapeutic targets and to improve brain repair strategies.
Lab Members
Florence Dô
Research Assistant
I am a research advisor with a scientific background that has spanned the pharmaceutical industry, contract research organizations (CROs), biotechnology, and now academia. In my current role, I share my expertise in both molecular and cellular biology, supporting team members in their projects. While I may not be the youngest in the group, I’ve had the advantage of seeing — and performing — techniques worthy of your lab manuals. Also, like a squirrel, if you ever need something, there’s a good chance I have it (or something close to it).
Florence Petit
Research Assistant
I’m a versatile research assistant who has been part of the lab for several years, combining scientific rigor, organizational skills, and a strong team spirit. A true Swiss Army knife of the lab, I juggle multiple roles: lab management (supplies and equipment maintenance), technical training (teaching basic methods such as biochemistry and cell culture), and research support (setting up and launching experimental protocols).
My specialty? Culturing iPS cells (induced pluripotent stem cells).
I often talk to myself — don’t worry! I’m probably on the phone or planning my day.
With a mix of efficiency, good humor, and professionalism, I help keep the lab running smoothly while contributing directly to the progress of our scientific projects.
Chiara Tocco, PhD
Postdoctoral Researcher
I’m a postdoctoral researcher interested in how sex differences influence microglia in aging and Parkinson’s disease. In the lab, I work with human iPSC-derived models and dive into techniques like immunocytochemistry and flow cytometry, immunological assays, and occasionally dip my toes in -omics analysis like bulk RNA-seq and mass spectrometry. Outside the lab, you’ll usually find me building or fixing something, knitting on a rainy day, or
chasing wildlife with my camera, or on my bike, sometimes both!
Students
Sandrine Armanville, MSc
PhD student
I am a PhD student in pharmaceutical sciences. My research project focuses on the direct neuronal reprogramming of astrocytes, with the goal of using it as an innovative cell therapy to replace neurons in neurological diseases affecting the cortex. To do this, I use an in vitro model of the human cortex: cortical organoids generated in the lab from induced pluripotent stem cells. My life revolves around mini-brains, running training sessions, and happy hour with friends. My hidden talent: combining all three in the same day.
Julie Bouquety, PharmD, MSc
PhD student
I am a PhD candidate with a background in pharmacy (PharmD), and my research focuses on understanding age-related changes in human astrocytes. To study these mechanisms, I use a direct conversion model that reprograms adult human fibroblasts into induced astrocytes termed iAs. My work investigates how aging impacts various aspects of astrocyte biology, including the unfolded protein response (UPR), calcium signaling, glutamate homeostasis, and neuron–astrocyte interactions. Through this approach, I aim to better understand how age-associated alterations in astrocyte function contribute to physiological aging but also the development and progression of neurodegenerative diseases.
Emilie Legault, MSc
PhD student
I am a 5th-year PhD student exploring how mitochondrial dysfunction shapes the fate of induced neurons derived from Parkinson’s disease patients. By dissecting the links between faulty energy metabolism and neuronal degeneration, I hope to uncover insights that could pave the way for new treatments. I’m known in the lab for my endless to-do lists and my habit of working far past closing time — science doesn’t watch the clock, and apparently neither do I. When I’m not at the bench, you’ll find me showing pictures of my cat to anyone, including those who didn’t ask.
Andrew Park, MSc
PhD student
I am a PhD student working on modulation of alpha-synuclein level using microRNAs. I use iPSCs derived brain organoids and 2D differentiation to generate disease's model. I also work to optimize the direct conversion using vectors to obtain dopaminergic neurons from fibroblasts. Cell culture is my life in the lab and I do lots of microscopy with a hint of qPCR for my analysis. Beside the lab, you will probably find me bouldering. If not, I will be wondering downtown with friends. Finally you should know that coffee is life, hope and dream!
Zaya Haj Mohamad
MSc student
I’m a master’s student studying the immune system in the context of Parkinson’s disease. Using iPSC-derived macrophages, immunopeptidomics, and Western blots, I explore how Parkinson’s disease–associated mutations alter the molecular profile of immune cells, revealing new links between the central nervous system and immunity. In my free time, I’m usually curled up with a book or film, or out exploring the city’s thrift shops and neighbourhoods!
Join Our Team
Are you passionate about neuroscience, aging, or cellular reprogramming?
We are always looking for motivated students, trainees, and research professionals to join our dynamic and collaborative lab environment.
Whether you’re interested in a MSc, PhD, postdoctoral position, or a research assistant role, we welcome applications from individuals with curiosity, initiative, and a drive to make a difference in Parkinson’s Disease research.
To apply:
📄 Send your CV and a brief cover letter outlining your background and interests to:
📧 janelle.drouin.ouellet@umontreal.ca
Please include “Join the Lab – [Your Name]” in the subject line.
We look forward to hearing from you!